Thrombotic Thrombocytopenic Purpura (TTP) is a life threatening, multisystem disease characterized by thrombocytopenia, microangiopathic hemolytic anemia, neurological changes, renal failure, and fever.These signs and symptoms are thought to be caused by microthrombi, composed of agglutinated platelets and fibrin, which deposit in the arterioles an
Objective: Worse neighborhood socioeconomic environment (NSEE) may contribute to an increased risk of type 2 diabetes (T2D).We examined whether the relationship between NSEE and T2D differs by sex and age in three study populations.Research design and methods: We conducted a harmonized analysis using data from three independent longitudinal study s
Transient receptor potential (TRP) channels are broadly implicated in the developmental programs of most tissues.Amongst these tissues, skeletal muscle and adipose are noteworthy for being essential in establishing systemic metabolic balance.TRP channels respond to environmental stimuli by supplying intracellular calcium that instigates plastic mas
To endow the immune system with the capacity to fight cancer has always attracted attention, although the clinical results obtained have been until recently disappointing.Cutaneous plastic masquerade masks melanoma is a highly immunogenic tumor; therefore most of the attempts to produce cancer vaccines have been addressed to this disease.New advanc
Introduction Antimicrobial resistance (AMR) has emerged as one of the leading threats to public health.AMR possesses a multidimensional challenge that has social, economic, and environmental dimensions that encompass the food production system, influencing human and animal health.The One Health approach highlights the inextricable linkage and inter